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Targeting Alzheimer's disease with gene and cell therapies

27 Mar 2018

Abstract excerpt

Alzheimer's disease (AD) causes dementia in both young and old people affecting more than 40 million people worldwide. The two neuropathological hallmarks of the disease, amyloid beta (Aβ) plaques and neurofibrillary tangles consisting of protein tau are considered the major contributors to the disease. However, a more complete picture reveals significant neurodegeneration and decreased cell survival,...

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PMID: 29582495
DOI: 10.1111/joim.12759

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