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Article

Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis.

Clinical genetics - 1 Apr 2006

Zintzaras E

Abstract excerpt

The methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been linked to the risk of developing breast cancer. A meta-analysis of 18 case-control studies investigating the association between the C677T and the A1298C polymorphisms of the MTHFR gene and breast cancer (BC) was carried out. The meta-analysis included genotype data on 5467/7336 and 3768/5276 cases/controls for C677T and A1298C,...

Topics

Breast Neoplasms
Case-Control Studies
Female
Genetic Predisposition to Disease
Genetics, Population
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Odds Ratio
Polymorphism, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16630166
DOI: 10.1111/j.1399-0004.2006.00605.x

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis.PMID 16630166Read ↗

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