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Article

Is it time to switch to a formulation other than the live attenuated poliovirus vaccine to prevent poliomyelitis?

8 Jan 2024

Abstract excerpt

The polioviruses (PVs) are mainly transmitted by direct contact with an infected person through the fecal-oral route and respiratory secretions (or more rarely via contaminated water or food) and have a primary tropism for the gut. After their replication in the gut, in rare cases (far less than 1% of the infected individuals), PVs can spread to the central nervous system leading to flaccid paralysis, which can...

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Identifiers

PMID: 38259741
DOI: 10.3389/fpubh.2023.1284337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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