Article
Strain classification of Mycobacterium tuberculosis isolates in Brazil based on genotypes obtained by spoligotyping, mycobacterial interspersed repetitive unit typing and the presence of large sequence and single nucleotide polymorphism.
PloS one - 1 Jan 2014
Vasconcellos Sidra E G, Acosta Chyntia Carolina, Gomes Lia Lima, Conceição Emilyn Costa, Lima Karla Valéria, de Araujo Marcelo Ivens, Leite Maria de Lourdes, Tannure Flávio, Caldas Paulo Cesar de Souza, Gomes Harrison M, Santos Adalberto Rezende, Gomgnimbou Michel K, Sola Christophe, Couvin David, Rastogi Nalin, Boechat Neio, Suffys Philip Noel
Abstract excerpt
Rio de Janeiro is endemic for tuberculosis (TB) and presents the second largest prevalence of the disease in Brazil. Here, we present the bacterial population structure of 218 isolates of Mycobacterium tuberculosis, derived from 186 patients that were diagnosed between January 2008 and December 2009. Genotypes were generated by means of spoligotyping, 24 MIRU-VNTR typing and presence of fbpC103, RDRio and RD174....
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