Article
The forest behind the tree: phylogenetic exploration of a dominant Mycobacterium tuberculosis strain lineage from a high tuberculosis burden country.
PloS one - 25 Mar 2011
Cardoso Oelemann Maranibia, Gomes Harrison M, Willery Eve, Possuelo Lia, Batista Lima Karla Valéria, Allix-Béguec Caroline, Locht Camille, Goguet de la Salmonière Yves-Olivier L, Gutierrez Maria Cristina, Suffys Philip, Supply Philip
Abstract excerpt
BACKGROUND: Genotyping of Mycobacterium tuberculosis isolates is a powerful tool for epidemiological control of tuberculosis (TB) and phylogenetic exploration of the pathogen. Standardized PCR-based typing, based on 15 to 24 mycobacterial interspersed repetitive unit-variable number of tandem repeat (MIRU-VNTR) loci combined with spoligotyping, has been shown to have adequate resolution power for tracing TB...
Topics
- Bacterial Typing Techniques
- Brazil
- Cluster Analysis
- Cost of Illness
- Genome, Bacterial
- Genotype
- Geography
- Humans
- Minisatellite Repeats
- Mycobacterium tuberculosis