Article
Genetic diversity of Mycobacterium tuberculosis isoniazid monoresistant and multidrug-resistant in Rio Grande do Sul, a tuberculosis high-burden state in Brazil.
Tuberculosis (Edinburgh, Scotland) - 1 May 2018
Esteves Leonardo Souza, Dalla Costa Elis Regina, Vasconcellos Sidra Ezidio Gonçalves, Vargas Andrei, Ferreira Junior Sérgio Luis Montego, Halon Maria Laura, Ribeiro Marta Osorio, Rodenbusch Rodrigo, Gomes Harrison Magdinier, Suffys Philip N, Rossetti Maria Lucia R
Abstract excerpt
Tuberculosis (TB) remains a major public health problem in the world and Brazil is among the countries with the highest incidence and prevalence rates, and Rio Grande do Sul, a Brazilian state, occupy a prominent position. Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) further aggravates this scenario, making it more difficult to treat and control the disease. Isoniazid monoresistance (IMR) may increase...
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