Article
Comparison of three molecular typing methods to assess genetic diversity for Mycobacterium tuberculosis.
Journal of microbiological methods - 1 Apr 2013
Pitondo-Silva André, Santos Adolfo Carlos Barreto, Jolley Keith A, Leite Clarice Queico Fujimura, Darini Ana Lúcia da Costa
Abstract excerpt
This study describes the comparison of three methods for genotyping of Mycobacterium tuberculosis, namely MIRU-VNTR (mycobacterial interspersed repetitive units-variable number of tandem repeats), spoligotyping and, for the first time, MLST (Multilocus Sequence Typing). In order to evaluate the discriminatory power of these methods, a total of 44 M. tuberculosis isolates obtained from sputum specimens of patients...
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