Article
Prospective genotyping of Mycobacterium tuberculosis from fresh clinical samples.
PloS one - 1 Jan 2014
Bidovec-Stojkovič Urška, Seme Katja, Žolnir-Dovč Manca, Supply Philip
Abstract excerpt
Shorter time-to-result is key for improving molecular-guided epidemiological investigation of tuberculosis (TB) cases. We performed a prospective study to evaluate the use of standardized MIRU-VNTR (mycobacterial interspersed repetitive-unit-variable-number tandem-repeat) typing of Mycobacterium tuberculosis directly on 79 fresh clinical samples from 26 TB patients consecutively enrolled over a 17-month period....
Topics
- Alleles
- DNA, Bacterial
- Genetic Loci
- Genotype
- Humans
- Minisatellite Repeats
- Mycobacterium tuberculosis
- Polymerase Chain Reaction
- Prospective Studies
- Severity of Illness Index
- Tuberculosis
