Article
Evaluation of large genotypic Mycobacterium tuberculosis clusters: contributions from remote and recent transmission.
Tuberculosis (Edinburgh, Scotland) - 1 Dec 2013
Teeter Larry D, Ha Ngan P, Ma Xin, Wenger Jane, Cronin Wendy A, Musser James M, Graviss Edward A
Abstract excerpt
Tuberculosis genotypic clustering is used as a proxy for recent transmission. The association between clustering and recent transmission becomes problematic when the genotyping method lacks specificity in defining a cluster, as well as for clusters with extensive jurisdictional histories and/or common genotypes. We investigated the four largest spoligotype/12 loci MIRU-VNTR-defined clusters in Harris County,...
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