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Article

High within-host diversity found from direct genotyping on post-mortem tuberculosis specimens in a high-burden setting.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Oct 2021

Rodríguez-Grande Cristina, Hurtado Juan Carlos, Rodríguez-Maus Sandra, Casas Isaac, Castillo Paola, Navarro Mireia, Rakislova Natalia, García-Basteiro Alberto, Carrilho Carla, Fernandes Fabiola, Lovane Lucilia, Jordao Dercio, Ismail Mamudo R, Lorenzoni Cesaltina, Cossa Anélsio, Mandomando Inácio, Bassat Quique, Menéndez Clara, Ordi Jaume, Muñoz Patricia, Pérez-Lago Laura, García de Viedma Darío, Martínez Miguel J

Abstract excerpt

OBJECTIVES: To characterize the clonal complexity in Mycobacterium tuberculosis (MTB) infections considering factors that help maximize the detection of coexisting strains/variants. METHODS: Genotypic analysis by Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeats (MIRU-VNTR) was performed directly on 70 biopsy specimens from two or more different tissues involving 28 tuberculosis cases...

Topics

Alleles
Autopsy
Genotype
Humans
Minisatellite Repeats
Mozambique
Mycobacterium tuberculosis
Tuberculosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34119641
DOI: 10.1016/j.cmi.2021.05.038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34119641-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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