Article
Evaluation of 24-locus MIRU-VNTR genotyping in Mycobacterium tuberculosis cluster investigations in four jurisdictions in the United States, 2006-2010.
Tuberculosis (Edinburgh, Scotland) - 1 Sept 2017
Teeter Larry D, Kammerer J Steven, Ghosh Smita, Nguyen Duc T M, Vempaty Padmaja, Tapia Jane, Miramontes Roque, Cronin Wendy A, Graviss Edward A
Abstract excerpt
The U.S. Centers for Disease Control and Prevention (CDC) uses a combination of spacer oligonucleotide typing (spoligotyping) and mycobacterial interspersed repetitive units-variable number of tandem repeats (MIRU-VNTR) analyses as part of the National TB Genotyping Service (NTGS). The NTGS expansion from 12-locus MIRU-VNTR (MIRU12) to 24-locus MIRU-VNTR (MIRU24) in 2009 enhanced the ability to discriminate...
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