Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of aminoacyl-tRNA synthetases gene polymorphisms with the risk of congenital heart disease in the Chinese Han population.

PloS one - 1 Jan 2014

Da Min, Feng Yu, Xu Jing, Hu Yuanli, Lin Yuan, Ni Bixian, Qian Bo, Hu Zhibin, Mo Xuming

Abstract excerpt

Aminoacyl-tRNA synthetases (ARSs) are in charge of cellular protein synthesis and have additional domains that function in a versatile manner beyond translation. Eight core ARSs (EPRS, MRS, QRS, RRS, IRS, LRS, KRS, DRS) combined with three nonenzymatic components form a complex known as multisynthetase complex (MSC).We hypothesize that the single-nucleotide polymorphisms (SNPs) of the eight core ARS coding genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acyl-tRNA Synthetases
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethnicity

Share to Genetic Association Studies

Share to Haplotypes

Share to Heart Defects, Congenital

Share to Multienzyme Complexes

Share to Open Reading Frames

Source

Open in PubMed Open full text

Identifiers

PMID: 25310850
DOI: 10.1371/journal.pone.0110072
PMCID: PMC4195700

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of aminoacyl-tRNA synthetases gene polymorphisms with the risk of congenital heart disease in the Chinese Han population.PMID 25310850Read ↗

Association of DARS gene polymorphisms with the risk of isolated ventricular septal defects in the Chinese Han population.Semantic proximity Read ↗

Potentially functional polymorphisms in aminoacyl-tRNA synthetases genes are associated with breast cancer risk in a Chinese population.Semantic proximity Read ↗

Aminoacyl tRNA synthetases and their connections to disease.Semantic proximity Read ↗

Genetic variants in multisynthetase complex genes are associated with DNA damage levels in Chinese populations.Semantic proximity Read ↗

The Role of Nuclear-Encoded Mitochondrial tRNA Charging Enzymes in Human Inherited Disease.Semantic proximity Read ↗

Aminoacyl-tRNA synthetases in medicine and disease.Semantic proximity Read ↗

Phenylalanyl-tRNA synthetase deficiency caused by biallelic variants in FARSA gene and literature review.Semantic proximity Read ↗

Aminoacyl-tRNA synthetases: Structure, function, and drug discovery.Semantic proximity Read ↗

Relationship between the acylation-stimulating protein gene and coronary heart disease in the Xinjiang Uygur and Han populations of China.Semantic proximity Read ↗

[Mutations in aminoacyl-tRNA synthetase genes: an analysis of 10 cases].Semantic proximity Read ↗

Association of MTR gene polymorphisms with the occurrence of non-syndromic congenital heart disease: a case-control study.Semantic proximity Read ↗

The role of aminoacyl-tRNA synthetases in genetic diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.