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Article

Association of MTR gene polymorphisms with the occurrence of non-syndromic congenital heart disease: a case-control study.

Scientific reports - 9 Jun 2023

Liu Yiping, Zhong Taowei, Song Xinli, Zhang Senmao, Sun Mengting, Wei Jianhui, Shu Jing, Yang Tubao, Wang Tingting, Qin Jiabi

Abstract excerpt

To exhaustively explore the association of infant genetic polymorphisms of methionine synthase (MTR) gene with the risk of non-syndromic congenital heart disease (CHD). A hospital-based case-control study involving 620 CHD cases and 620 health controls was conducted from November 2017 to March 2020. Eighteen SNPs were detected and analyzed. Our date suggested that the genetic polymorphisms of MTR gene at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37296303
DOI: 10.1038/s41598-023-36330-x
PMCID: PMC10256807

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