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Article

Association of DARS gene polymorphisms with the risk of isolated ventricular septal defects in the Chinese Han population.

Italian journal of pediatrics - 21 Nov 2016

Feng Yu, Chen Runsen, Mo Xuming

Abstract excerpt

BACKGROUND: Ventricular septal defects (VSD) are the most common subtype of congenital heart defects (CHD) and are estimated to account for 20 to 30% of all cases of CHD. The etiology of isolated VSD remains poorly understood. Eight core aminoacyl-tRNA synthetases (ARSs) (EPRS, MARS, QARS, RARS, IARS, LARS, KARS, and DARS) combine with three nonenzymatic components to form a complex known as the multisynthetase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27871331
DOI: 10.1186/s13052-016-0311-2
PMCID: PMC5117545

Genes

MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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