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Article

Association of base excision repair gene polymorphisms with ESRD risk in a Chinese population.

Oxidative medicine and cellular longevity - 1 Jan 2012

Cai Zhenming, Chen Huimei, Tao Jing, Guo Wenwen, Liu Xiufang, Zheng Bixia, Sun Wei, Wang Yaping

Abstract excerpt

The base excision repair (BER) pathway, containing OGG1, MTH1 and MUTYH, is a major protector from oxidative DNA damage in humans, while 8-oxoguanine (8-OHdG), an index of DNA oxidation, is increased in maintenance hemodialysis (HD) patients. Four polymorphisms of BER genes, OGG1 c.977C > G (rs10...

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Source

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Identifiers

PMID: 22720119
DOI: 10.1155/2012/928421
PMCID: PMC3375099

Genes

MUTYH
OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22720119-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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