Article
Host genetic studies in adult pulmonary tuberculosis.
Seminars in immunology - 1 Dec 2014
Meyer Christian G, Thye Thorsten
Abstract excerpt
Early observations, candidate gene studies and, more recently, genome-wide association studies have shown that susceptibility to tuberculosis has a host genetic component. Because the value of candidate gene studies has been doubted due to major limitations such as lack of sufficient power and small study groups, lack of reproducibility in independent groups and, often, ambiguous or even contrasting results in...
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