Article
Genetic epidemiology of tuberculosis susceptibility: impact of study design.
PLoS pathogens - 20 Jan 2011
Stein Catherine M
Abstract excerpt
Several candidate gene studies have provided evidence for a role of host genetics in susceptibility to tuberculosis (TB). However, the results of these studies have been very inconsistent, even within a study population. Here, we review the design of these studies from a genetic epidemiological perspective, illustrating important differences in phenotype definition in both cases and controls, consideration of...
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