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Pluripotent Stem Cell miRNAs and Metastasis in Invasive Breast Cancer

11 Oct 2014

Abstract excerpt

BACKGROUND: The purpose of this study is to determine whether microRNA for pluripotent stem cells are also expressed in breast cancer and are associated with metastasis and outcome. METHODS: We studied global microRNA profiles during differentiation of human embryonic stem cells (n =26) and in breast cancer patients (n = 33) and human cell lines (n = 35). Using in situ hybridization, we then investigated MIR302...

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PMID: 25306216
DOI: 10.1093/jnci/dju324

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