Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists

13 Oct 2017

Abstract excerpt

MicroRNA-mediated post-transcriptional regulation plays key roles in stem cell self-renewal and tumorigenesis. However, the in vivo functions of specific microRNAs in controlling mammary stem cell (MaSC) activity and breast cancer formation remain poorly understood. Here we show that miR-31 is highly expressed in MaSC-enriched mammary basal cell population and in mammary tumors, and is regulated by NF-κB...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Circular RNAs in diseases
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29051494
DOI: 10.1038/s41467-017-01059-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonistsPMID 29051494Read ↗

Effects of miRNAs on functions of breast cancer stem cells and treatment of breast cancerSemantic proximity Read ↗

MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/β-catenin pathway.Semantic proximity Read ↗

Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancerSemantic proximity Read ↗

MicroRNAs, a subpopulation of regulators, are involved in breast cancer progression through regulating breast cancer stem cells (Review)Semantic proximity Read ↗

MicroRNA Regulation of Breast Cancer StemnessSemantic proximity Read ↗

Comparative Analysis of microRNAs that Stratify in vitro Mammary stem and Progenitor Activity Reveals Functionality of Human miR-92b-3pSemantic proximity Read ↗

Mammary gland stem cells and their application in breast cancer.Semantic proximity Read ↗

Unraveling the Potential of miRNAs from CSCs as an Emerging Clinical Tool for Breast Cancer Diagnosis and PrognosisSemantic proximity Read ↗

MicroRNAs, a Promising Target for Breast Cancer Stem Cells.Semantic proximity Read ↗

Analysis of microRNA expression in canine mammary cancer stem-like cells indicates epigenetic regulation of transforming growth factor-beta signaling.Semantic proximity Read ↗

Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5aSemantic proximity Read ↗

Role of microRNAs in the Regulation of Breast Cancer Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.