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Article

IL6 genotype, tumour ER-status, and treatment predicted disease-free survival in a prospective breast cancer cohort.

BMC cancer - 11 Oct 2014

Markkula Andrea, Simonsson Maria, Ingvar Christian, Rose Carsten, Jernström Helena

Abstract excerpt

BACKGROUND: In breast cancer, high levels of the inflammatory cytokine interleukin-6 (IL-6) have been associated with disease-free survival and treatment resistance. Increased serum levels of IL-6 have been correlated with increased levels of NF-κβ and aromatase expression in adipose tissue. Several IL6 single nucleotide polymorphisms have been associated with breast cancer prognosis, but the impact may differ...

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Identifiers

PMID: 25305747
DOI: 10.1186/1471-2407-14-759
PMCID: PMC4198733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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