Article
Genotypic and haplotype analysis of Interleukin-6 and -18 gene polymorphisms in association with clinicopathological factors in breast cancer.
Cytokine - 1 Dec 2022
Padala Chiranjeevi, Puranam Kaushik, Shyamala Nivas, Kupsal Keerthi, Kummari Ramanjaneyulu, Galimudi Rajesh Kumar, Gundapaneni Kishore Kumar, Tupurani Mohini Aiyengar, Suryadevera Aparna, Chinta Sanjeeva Kumari, Manavathi Bramanandam, Hanumanth Surekha Rani
Abstract excerpt
Cytokines are multifunctional glycoproteins that play a vital role in the tumor microenvironment and progression of breast cancer. Genetic polymorphisms may influence the immune responses restrained by pro- and anti-inflammatory cytokine expression in tumors. Hence, the present study evaluated the contribution of Interleukin (IL) 6 (rs1800797, rs1800796, and rs1800795) and IL18 (rs1946518, rs187238, and )...
