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Article

Interleukin-1 and interleukin-6 gene polymorphisms and the risk of breast cancer in caucasian women.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2005

Hefler Lukas A, Grimm Christoph, Lantzsch Tilmann, Lampe Dieter, Leodolter Sepp, Koelbl Heinz, Heinze Georg, Reinthaller Alexander, Tong-Cacsire Dan, Tempfer Clemens, Zeillinger Robert

Abstract excerpt

PURPOSE: Genetic polymorphisms of cytokine-encoding genes are known to predispose to malignant disease. Interleukin (IL)-1 and IL-6 are crucially involved in breast carcinogenesis. Whether polymorphisms of the genes encoding IL-1 (IL1) and IL-6 (IL6) also influence breast cancer risk is unknown. EXPERIMENTAL DESIGN: In the present case-control study, we ascertained three polymorphisms of the IL1 gene cluster...

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PMID: 16115908
DOI: 10.1158/1078-0432.CCR-05-0001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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