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Article

Effects of Infection-Induced Fever and the Interaction with IL6 rs1800796 Polymorphism on the Prognosis of Breast Cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 2 Nov 2022

Ye Hengming, Tang Lu-Ying, Liang Zhuo-Zhi, Chen Qian-Xin, Li Yun-Qian, Liu Qiang, Xie Xiaoming, Lin Ying, Ren Ze-Fang

Abstract excerpt

BACKGROUND: Previous studies have found that acute febrile infection may decrease the risk of breast cancer. Meanwhile, it is well known that interleukin-6 (IL6) played dual roles in the tumor microenvironment. Fever may stimulate IL6 production, and IL6 rs1800796 also influences the expression of IL6. However, the impact of fever and its interaction with IL6 rs1800796 on breast cancer survival remains to be...

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PMID: 36084325
DOI: 10.1158/1055-9965.EPI-22-0498

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