Article
RASSF1A promoter hypermethylation is a strong biomarker of poor survival in patients with salivary adenoid cystic carcinoma in a Chinese population.
PloS one - 1 Jan 2014
Zhang Chun-Ye, Zhao Yang-Xing, Xia Rong-Hui, Han Jing, Wang Bing-Shun, Tian Zhen, Wang Li-Zhen, Hu Yu-Hua, Li Jiang
Abstract excerpt
In addition to the clinicopathological parameters, molecular biomarkers are becoming increasingly important in the prognostic evaluation of cancer patients. This study aimed to determine the molecular alterations in the RAS association domain family protein1A gene (RASSF1A) in salivary adenoid cystic carcinoma (ACC) and to evaluate the potential of such alterations as prognostic markers. One hundred and...
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