Article
Promoter methylation of <i>p16</i><sup><i>INK4a</i></sup>, <i>RASSF1A</i>, and <i>DAPK</i> is frequent in salivary adenoid cystic carcinoma
15 Jun 2005
Abstract excerpt
BACKGROUND: Promoter methylation is a common mechanism of inactivation of tumor suppressor genes in multiple tumor types. However, little is known about its role in the development of adenoid cystic carcinoma of the salivary gland (ACC). In the current study, the authors investigated whether promoter methylation is common in ACC and whether it may influence ACC development. METHODS: The promoter methylation...
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