Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constitutive NF-κB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice

24 Aug 2005

Abstract excerpt

Human herpesvirus 8 (HHV-8, also called Kaposi's sarcoma-associated herpes virus) has been linked to Kaposi's sarcoma and primary effusion lymphoma. HHV-8-encoded viral Fas-associated death domain-like IL-1-converting enzyme inhibitory protein (vFLIP) is one of the few viral proteins to be expressed in latently infected cells and plays a key role in the survival and proliferation of primary effusion lymphoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16120683
DOI: 10.1073/pnas.0408577102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constitutive NF-κB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic micePMID 16120683Read ↗

Tumorigenesis and Aberrant Signaling in Transgenic Mice Expressing the Human Herpesvirus-8 K1 GeneSemantic proximity Read ↗

Activation of alternative NF-κB pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1β-converting enzyme inhibitory protein (vFLIP)Semantic proximity Read ↗

NF-κB is essential for the progression of KSHV- and EBV-infected lymphomas in vivoSemantic proximity Read ↗

The Human Herpes Virus 8-encoded Viral FLICE Inhibitory Protein Physically Associates with and Persistently Activates the IκB Kinase ComplexSemantic proximity Read ↗

The Inhibitor of Death Receptor Signaling, Flice-Inhibitory Protein Defines a New Class of Tumor Progression FactorsSemantic proximity Read ↗

Mechanism of Fas signaling regulation by human herpesvirus 8 K1 oncoprotein.Semantic proximity Read ↗

Lymphoid hyperplasia and lymphoma in KSHV K1 transgenic mice.Semantic proximity Read ↗

Kaposi sarcoma herpesvirus (KSHV) vFLIP oncoprotein induces B cell transdifferentiation and tumorigenesis in miceSemantic proximity Read ↗

Induction of IL-8 expression by human herpesvirus 8 encoded vFLIP K13 via NF-κB activationSemantic proximity Read ↗

Kaposi Sarcoma herpesvirus reactivation and replication are dispensable for cell-lineage specific tumorigenesis in whole genome transgenic miceSemantic proximity Read ↗

An alternative Kaposi's sarcoma-associated herpesvirus replication program triggered by host cell apoptosis.Semantic proximity Read ↗

The viral interferon-regulatory factor-3 is required for the survival of KSHV-infected primary effusion lymphoma cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.