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Article

Primary lymphocyte infection models for KSHV and its putative tumorigenesis mechanisms in B cell lymphomas

28 Apr 2017

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) is the latest addition to the human herpesvirus family. Unlike alpha- and beta-herpesvirus subfamily members, gamma-herpesviruses, including Epstein-Barr virus (EBV) and KSHV, cause various tumors in humans. KSHV primarily infects endothelial and B cells in vivo, and is associated with at least three malignancies: Kaposi's sarcoma and two B cell lymphomas,...

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PMID: 28455586
DOI: 10.1007/s12275-017-7075-2

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