Article
Renal phenotype of UT-A urea transporter knockout mice.
Journal of the American Society of Nephrology : JASN - 1 Jun 2005
Fenton Robert A, Flynn Anneliese, Shodeinde Adetola, Smith Craig P, Schnermann Jurgen, Knepper Mark A
Abstract excerpt
The urea transporters UT-A1 and UT-A3 mediate rapid transepithelial urea transport across the inner medullary collecting duct (IMCD). In a previous study, using a new mouse model in which both UT-A1 and UT-A3 were genetically deleted from the IMCD (UT-A1/3(-/-) mice), we investigated the role of...
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