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Article

Soluble factors from colonic epithelial cells contribute to gut homeostasis by modulating macrophage phenotype.

Innate immunity - 1 May 2015

Kristek Maja, Collins Laura E, DeCourcey Joseph, McEvoy Fiona A, Loscher Christine E

Abstract excerpt

Intestinal macrophages originate from inflammatory blood monocytes which migrate to the intestine, where they differentiate into anti-inflammatory macrophages through a number of transitional stages. These macrophages typically remain hypo-responsive to commensal bacteria and food Ags in the intestine, yet also retain the ability to react to invading pathogens. In this study we examined the role of epithelial...

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PMID: 25298104
DOI: 10.1177/1753425914538294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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