Article
Genetic polymorphisms of interleukin 20 (IL-20) in patients with ulcerative colitis.
Immunology letters - 1 Jan 2013
Yamamoto-Furusho Jesús K, De-León-Rendón Jorge L, de la Torre Monica García, Alvarez-León Edith, Vargas-Alarcón Gilberto
Abstract excerpt
Interleukin (IL)-20 belongs to the IL-10 family and is a potent immunomodulatory cytokine with implications for pathogenesis in the inflammatory bowel disease (IBD). The interleukin 20 gene is located within a 200kb region of q31-32 locus of chromosome 1. No previous studies have reported this novel association between ulcerative colitis (UC) and IL-20 polymorphisms. In the present work, we evaluated the role of...
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