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Article

New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.

The Journal of biological chemistry - 14 Nov 2014

Guarino Carla, Legowska Monika, Epinette Christophe, Kellenberger Christine, Dallet-Choisy Sandrine, Sieńczyk Marcin, Gabant Guillaume, Cadene Martine, Zoidakis Jérôme, Vlahou Antonia, Wysocka Magdalena, Marchand-Adam Sylvain, Jenne Dieter E, Lesner Adam, Gauthier Francis, Korkmaz Brice

Abstract excerpt

The function of neutrophil protease 3 (PR3) is poorly understood despite of its role in autoimmune vasculitides and its possible involvement in cell apoptosis. This makes it different from its structural homologue neutrophil elastase (HNE). Endogenous inhibitors of human neutrophil serine proteas...

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Identifiers

PMID: 25288799
DOI: 10.1074/jbc.M114.591339
PMCID: PMC4231656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25288799-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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