Article
NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2013
Perera Natascha C, Wiesmüller Karl-Heinz, Larsen Maria Torp, Schacher Beate, Eickholz Peter, Borregaard Niels, Jenne Dieter E
Abstract excerpt
Whereas neutrophil elastase, cathepsin G, and proteinase 3 have been known as granule-associated serine proteases of neutrophils for decades, a fourth member, called neutrophil serine protease 4 (NSP4), was just recently described and provisionally characterized. In this study, we identified NSP4...
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