Article
Nogo-A deletion increases the plasticity of the optokinetic response and changes retinal projection organization in the adult mouse visual system.
Brain structure & function - 1 Jan 2016
Guzik-Kornacka Anna, van der Bourg Alexander, Vajda Flora, Joly Sandrine, Christ Franziska, Schwab Martin E, Pernet Vincent
Abstract excerpt
The inhibitory action of Nogo-A on axonal growth has been well described. However, much less is known about the effects that Nogo-A could exert on the plasticity of neuronal circuits under physiological conditions. We investigated the effects of Nogo-A knock-out (KO) on visual function of adult mice using the optokinetic response (OKR) and the monocular deprivation (MD)-induced OKR plasticity and analyzed the...
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