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Article

Ebf1 deficiency causes increase of Müller cells in the retina and abnormal topographic projection at the optic chiasm.

Biochemical and biophysical research communications - 28 Oct 2011

Jin Kangxin, Xiang Mengqing

Abstract excerpt

The Ebf transcription factors play important roles in the developmental processes of many tissues. We have shown previously that four members of the Ebf family are expressed during mouse retinal development and are both necessary and sufficient to specify multiple retinal cell fates. Here we describe the changes in cell differentiation and retinal ganglion cell (RGC) projection in Ebf1 knockout mice. Analysis of...

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Identifiers

PMID: 21971554
DOI: 10.1016/j.bbrc.2011.09.108
PMCID: PMC3205217

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