Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Failure to maintain eye-specific segregation in nob, a mutant with abnormally patterned retinal activity.

Neuron - 20 Apr 2006

Demas Jay, Sagdullaev Botir T, Green Erick, Jaubert-Miazza Lisa, McCall Maureen A, Gregg Ronald G, Wong Rachel O L, Guido William

Abstract excerpt

Axon terminals from the two eyes initially overlap in the dorsal-lateral geniculate nucleus (dLGN) but subsequently refine to occupy nonoverlapping territories. Retinal activity is required to establish and maintain this segregation. We show that despite the presence of retinal activity, segregated projections desegregate when the structure of activity is altered. Early in development, spontaneous retinal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Brain Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Image Processing, Computer-Assisted

Share to Mice, Mutant Strains

Share to Proteoglycans

Share to Retina

Share to Retinal Ganglion Cells

Share to Visual Pathways

Source

Identifiers

PMID: 16630836
DOI: 10.1016/j.neuron.2006.03.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Failure to maintain eye-specific segregation in nob, a mutant with abnormally patterned retinal activity.PMID 16630836Read ↗

Restricted perinatal retinal degeneration induces retina reshaping and correlated structural rearrangement of the retinotopic map.Semantic proximity Read ↗

POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification.Semantic proximity Read ↗

Modeling development in retinal afferents: retinotopy, segregation, and ephrinA/EphA mutants.Semantic proximity Read ↗

Rod bipolar cells and horizontal cells form displaced synaptic contacts with rods in the outer nuclear layer of the nob2 retina.Semantic proximity Read ↗

Evidence for an instructive role of retinal activity in retinotopic map refinement in the superior colliculus of the mouse.Semantic proximity Read ↗

Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling.Semantic proximity Read ↗

A naturally occurring mouse model of X-linked congenital stationary night blindness.Semantic proximity Read ↗

Bone morphogenetic proteins, eye patterning, and retinocollicular map formation in the mouse.Semantic proximity Read ↗

Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.Semantic proximity Read ↗

N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites.Semantic proximity Read ↗

Dre - Cre sequential recombination provides new tools for retinal ganglion cell labeling and manipulation in mice.Semantic proximity Read ↗

Nogo-A deletion increases the plasticity of the optokinetic response and changes retinal projection organization in the adult mouse visual system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.