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Article

Short intronic repeat sequences facilitate circular RNA production.

Genes & development - 15 Oct 2014

Liang Dongming, Wilusz Jeremy E

Abstract excerpt

Recent deep sequencing studies have revealed thousands of circular noncoding RNAs generated from protein-coding genes. These RNAs are produced when the precursor messenger RNA (pre-mRNA) splicing machinery "backsplices" and covalently joins, for example, the two ends of a single exon. However, the mechanism by which the spliceosome selects only certain exons to circularize is largely unknown. Using extensive...

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Identifiers

PMID: 25281217
DOI: 10.1101/gad.251926.114
PMCID: PMC4201285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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