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Article

Paricalcitol reduces peritoneal fibrosis in mice through the activation of regulatory T cells and reduction in IL-17 production.

PloS one - 1 Jan 2014

González-Mateo Guadalupe T, Fernández-Míllara Vanessa, Bellón Teresa, Liappas Georgios, Ruiz-Ortega Marta, López-Cabrera Manuel, Selgas Rafael, Aroeira Luiz S

Abstract excerpt

Fibrosis is a significant health problem associated with a chronic inflammatory reaction. The precise mechanisms involved in the fibrotic process are still poorly understood. However, given that inflammation is a major causative factor, immunomodulation is a possible therapeutic approach to reduce fibrosis. The vitamin D receptor (VDR) that is present in all hematopoietic cells has been associated with...

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PMID: 25279459
DOI: 10.1371/journal.pone.0108477
PMCID: PMC4184804

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VDR
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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