Article
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC genomics - 3 Oct 2014
Didion John P, Buus Ryan J, Naghashfar Zohreh, Threadgill David W, Morse Herbert C, de Villena Fernando Pardo-Manuel
Abstract excerpt
BACKGROUND: The crisis of Misidentified and contaminated cell lines have plagued the biological research community for decades. Some repositories and journals have heeded calls for mandatory authentication of human cell lines, yet misidentification of mouse cell lines has received little publicity despite their importance in sponsored research. Short tandem repeat (STR) profiling is the standard authentication...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
