Article

Short Tandem Repeat Profiling via Next Generation Sequencing for Cell Line Authentication

2023-02-26

Abstract excerpt

Cell lines are indispensable models for modern biomedical research. In the era of CRISPR gene editing, they serve as versatile tools for preclinical studies, allowing patient specific mutations to be modeled or corrected and the resulting phenotypic outcomes studied. A large part of their usefulness derives from the ability of a cell line to proliferate over multiple passages (often indefinitely) allowing multiple...

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Literature Corpus work: 9d7cede4-a31e-517e-af4c-1633570f4d13
DOI: 10.1101/2023.02.25.530013

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