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Identification of a genetic contamination in a commercial mouse strain using two panels of polymorphic markers.

Laboratory animals - 1 Apr 2007

Nitzki F, Kruger A, Reifenberg K, Wojnowski L, Hahn H

Abstract excerpt

Rapid detection of genetic contamination is critical in mouse studies involving inbred strains. During a Quantitative Trait Locus (QTL) study using simple sequence length polymorphism (SSLP) markers, we noticed heterozygosity at some loci of a commercially available inbred C57BL/6N mouse strain, suggesting a contamination by another mouse strain. A panel of 100 single-nucleotide polymorphism (SNP) markers was...

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PMID: 17430621
DOI: 10.1258/002367707780378104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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