Article
Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse.
Genomics - 1 May 2004
Petkov Petko M, Cassell Megan A, Sargent Evelyn E, Donnelly Charles J, Robinson Phil, Crew Victor, Asquith Steven, Haar Raymond Vonder, Wiles Michael V
Abstract excerpt
We have developed a genotyping system for detecting genetic contamination in the laboratory mouse based on assaying single-nucleotide polymorphism (SNP) markers positioned on all autosomes and the X chromosome. This system provides a fast, reliable, and cost-effective way for genetic monitoring, while maintaining a very high degree of confidence. We describe the allelic distribution of 235 SNPs in 48 mouse...
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