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Genetic Insights into the Economic Toll of Cell Line Misidentification: A Comprehensive Review.

Medical sciences (Basel, Switzerland) - 5 Jan 2026

Weiskirchen Ralf

Abstract excerpt

Cell line misidentification, first exposed when HeLa cells were shown to contaminate dozens of "unique" cultures, now compromises roughly one in five lines and renders thousands of papers potentially unreliable, propagating unreliable data through hundreds of thousands of citations. The financial fallout is vast with irreproducible research linked to faulty cell stocks costing the United States an estimated $28...

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PMID: 41562915
DOI: 10.3390/medsci14010025
PMCID: PMC12821653

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