Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FPR1 interacts with CFH, HTRA1 and smoking in exudative age-related macular degeneration and polypoidal choroidal vasculopathy.

Eye (London, England) - 1 Dec 2014

Liang X Y, Chen L J, Ng T K, Tuo J, Gao J-L, Tam P O S, Lai T Y Y, Chan C-C, Pang C P

Abstract excerpt

PURPOSE: To determine the genetic association of an inflammation-related gene, formyl peptide receptor 1 (FPR1), in exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). METHODS: The coding region of FPR1 gene was sequenced in 554 unrelated Chinese individuals: 155 exudative AMD patients, 179 PCV patients, and 220 controls. Interactions and combined effects of FPR1 with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choroidal Neovascularization
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescein Angiography

Share to High-Temperature Requirement A Serine Peptidase 1

Share to Polyps

Share to Serine Endopeptidases

Share to Smoking

Share to Wet Macular Degeneration

Source

Open in PubMed Open full text

Identifiers

PMID: 25277308
DOI: 10.1038/eye.2014.226
PMCID: PMC4268466

Genes

FPR1
CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FPR1 interacts with CFH, HTRA1 and smoking in exudative age-related macular degeneration and polypoidal choroidal vasculopathy.PMID 25277308Read ↗

Genetic variants in three genes and smoking show strong associations with susceptibility to exudative age-related macular degeneration in a Chinese population.Semantic proximity Read ↗

Analysis of Genetic and Environmental Risk Factors and Their Interactions in Korean Patients with Age-Related Macular DegenerationSemantic proximity Read ↗

HTRA1 promoter variant differentiates polypoidal choroidal vasculopathy from exudative age-related macular degeneration.Semantic proximity Read ↗

HTRA1 variants in exudative age-related macular degeneration and interactions with smoking and CFH.Semantic proximity Read ↗

Correlation between CFH Y402H and HTRA1 rs11200638 genotype to typical exudative age-related macular degeneration and polypoidal choroidal vasculopathy phenotype in the Japanese population.Semantic proximity Read ↗

Polymorphisms in CFH, HTRA1 and CX3CR1 confer risk to exudative age-related macular degeneration in Han Chinese.Semantic proximity Read ↗

LOC387715/HTRA1 polymorphisms, smoking and combined effects on exudative age-related macular degeneration in a Korean population.Semantic proximity Read ↗

Association of CFH, LOC387715, and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population.Semantic proximity Read ↗

CFH (rs1061170, rs1410996), KDR (rs2071559, rs1870377) and KDR and CFH Serum Levels in AMD Development and Treatment EfficacySemantic proximity Read ↗

Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.Semantic proximity Read ↗

Joint effect of cigarette smoking and CFH and LOC387715/HTRA1 polymorphisms on polypoidal choroidal vasculopathy.Semantic proximity Read ↗

Differentiation of exudative age-related macular degeneration and polypoidal choroidal vasculopathy in the ARMS2/HTRA1 locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.