A genome-wide pleiotropy scan for prostate cancer risk.

doi:10.1016/j.eururo.2014.09.020

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Article

A genome-wide pleiotropy scan for prostate cancer risk.

European urology - 1 Apr 2015

Panagiotou Orestis A, Travis Ruth C, Campa Daniele, Berndt Sonja I, Lindstrom Sara, Kraft Peter, Schumacher Fredrick R, Siddiq Afshan, Papatheodorou Stefania I, Stanford Janet L, Albanes Demetrius, Virtamo Jarmo, Weinstein Stephanie J, Diver W Ryan, Gapstur Susan M, Stevens Victoria L, Boeing Heiner, Bueno-de-Mesquita H Bas, Barricarte Gurrea Aurelio, Kaaks Rudolf, Khaw Kay-Tee, Krogh Vittorio, Overvad Kim, Riboli Elio, Trichopoulos Dimitrios, Giovannucci Edward, Stampfer Meir, Haiman Christopher, Henderson Brian, Le Marchand Loic, Gaziano J Michael, Hunter David J, Koutros Stella, Yeager Meredith, Hoover Robert N, Chanock Stephen J, Wacholder Sholom, Key Timothy J, Tsilidis Konstantinos K

Abstract excerpt

BACKGROUND: No single-nucleotide polymorphisms (SNPs) specific for aggressive prostate cancer have been identified in genome-wide association studies (GWAS). OBJECTIVE: To test if SNPs associated with other traits may also affect the risk of aggressive prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: SNPs implicated in any phenotype other than prostate cancer (p≤10(-7)) were identified through the catalog of...

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Identifiers

PMID: 25277271
DOI: 10.1016/j.eururo.2014.09.020
PMCID: PMC4359641

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