Article
Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP.
Journal of the National Cancer Institute - 19 Dec 2007
Duggan David, Zheng Siqun L, Knowlton Michele, Benitez Debbie, Dimitrov Latchezar, Wiklund Fredrik, Robbins Christiane, Isaacs Sarah D, Cheng Yu, Li Ge, Sun Jielin, Chang Bao-Li, Marovich Leslie, Wiley Kathleen E, Bälter Katarina, Stattin Pär, Adami Hans-Olov, Gielzak Marta, Yan Guifang, Sauvageot Jurga, Liu Wennuan, Kim Jin Woo, Bleecker Eugene R, Meyers Deborah A, Trock Bruce J, Partin Alan W, Walsh Patrick C, Isaacs William B, Grönberg Henrik, Xu Jianfeng, Carpten John D
Abstract excerpt
BACKGROUND: The consistent finding of a genetic susceptibility to prostate cancer suggests that there are germline sequence variants predisposing individuals to this disease. These variants could be useful in screening and treatment. METHODS: We performed an exploratory genome-wide association sc...
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