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Article

Expression and regulation of LOXL1 and elastin-related genes in eyes with exfoliation syndrome.

Journal of glaucoma - 1 Jan 2000

Wiggs Janey L, Pasquale Louis R

Abstract excerpt

Variants in LOXL1 are significantly associated with exfoliation syndrome (XFS), however the impact of the associated variants on disease development is not yet understood. Initially the associated missense changes, R141L and G153D, were considered to be pathogenic alleles. Flipping of the risk allele in certain populations for both missense variants provided strong evidence that these missense changes are not...

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Source

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Identifiers

PMID: 25275910
DOI: 10.1097/IJG.0000000000000124
PMCID: PMC4540221

Genes

LOXL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression and regulation of LOXL1 and elastin-related genes in eyes with exfoliation syndrome.PMID 25275910Read ↗

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