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Article

Significance of BMPR2 mutations in pulmonary arterial hypertension.

Respiratory investigation - 1 Jul 2021

Tatius Bintang, Wasityastuti Widya, Astarini Fajar Dwi, Nugrahaningsih Dwi Aris Agung

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a debilitating disease that results from progressive remodeling and inflammation of pulmonary arteries. PAH develops gradually, is difficult to diagnose, and has a high mortality rate. Although mutation in the bone morphogenetic protein receptor 2 (BMPR2) gene has been identified as the main genetic cause of PAH, the underlying pathways involving the pathophysiology of PAH...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34023242
DOI: 10.1016/j.resinv.2021.03.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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