Article
Role of protein S deficiency in children with venous thromboembolism. An observational international cohort study.
Thrombosis and haemostasis - 1 Feb 2015
Klostermeier Ulrich C, Limperger Verena, Kenet Gili, Kurnik Karin, Alhenc Gelas Martine, Finckh Ulrich, Junker Ralf, Heller Christine, Zieger Barbara, Knöfler Ralf, Holzhauer Susanne, Mesters Rolf, Krümpel Anne, Nowak-Göttl Ulrike
Abstract excerpt
Venous thromboembolism [TE] is a multifactorial disease, and protein S deficiency [PSD] constitutes a major risk factor. In the present study the prevalence of PSD and the clinical presentation at TE onset in a cohort of children is reported. In 367 unselected paediatric patients with TE (age 0.1-18 years) recruited between July 1996 and December 2013, a comprehensive thrombophilia screening was performed along...
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