Article
Clinical and laboratory characteristics of children with venous thromboembolism and protein C-deficiency: an observational Israeli-German cohort study.
British journal of haematology - 1 Nov 2014
Limperger Verena, Klostermeier Ulrich C, Kenet Gili, Holzhauer Susanne, Alhenc Gelas Martine, Finckh Ulrich, Junker Ralf, Heller Christine, Zieger Barbara, Kurnik Karin, Knöfler Ralf, Mesters Rolf, Halimeh Susan, Nowak-Göttl Ulrike
Abstract excerpt
Venous thromboembolism [TE] is a multifactorial disease and protein C deficiency [PCD] constitutes a major risk factor. In the present study the prevalence of PCD and the clinical presentation at TE onset, including neonatal purpura fulminans, in a cohort of children are reported. In 367 unselected children (0·1-19 years) recruited between July 1996 and December 2013, a comprehensive thrombophilia screening was...
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