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Article

PROS1 genotype phenotype relationships in a large cohort of adults with suspicion of inherited quantitative protein S deficiency.

Thrombosis and haemostasis - 1 Mar 2016

Alhenc-Gelas Martine, Plu-Bureau Genevieve, Horellou Marie Hélène, Rauch Antoine, Suchon Pierre

Abstract excerpt

Inherited protein S deficiency (PSD) is an established risk factor for venous thromboembolism (VTE). However, data are conflicting concerning risk of VTE associated with decreased free PS level (FPS) and information on PROS1 genotype-phenotype relationship is sparse. In a retrospective cohort of 579 patients with inherited type I/III deficiency suspicion, PROS1 genotyping was performed and the effect of genotype...

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Identifiers

PMID: 26466767
DOI: 10.1160/TH15-05-0391

Genes

PROS1
PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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